Table 2 Comparisons of HBP and HBPc dynamic monitoring levels between survivors and nonsurvivors in patients with sepsis or septic shock.

From: Dynamic changes in heparin-binding protein as a prognostic biomarker for 30-day mortality in sepsis patients in the intensive care unit

Variables

Survivors (N = 137)

Non-survivors (N = 69)

p-value

HBP-initial (ng/mL) median (IQR)

117 (75–185)

234 (203–276)

 < 0.001

HBP-24 h (ng/mL) median (IQR)

85 (51–120)

188 (141–197)

 < 0.001

HBP-48 h (ng/mL) median (IQR)

48 (24–86)

207 (151–210)

 < 0.001

HBPc-24 h (%) median (IQR)

− 28 (− 42, − 17)

− 22 (− 34, − 14)

0.018

HBPc-48 h (%) median (IQR)

− 54 (− 72, − 36)

− 15 (− 38, − 3)

 < 0.001

  1. HBP-initial, HBP level at admission. HBP-24 h, HBP level at 24 h. HBP-48 h, HBP level at 48 h. HBPc-24 h (%), changes in HBP levels between baseline and 24 h, presented as percentages. HBPc-48 h (%), changes in HBP levels between baseline and 48 h, presented as percentages.
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