Figure 8
From: The stimulatory effect of fusobacteria on dendritic cells under aerobic or anaerobic conditions
Comparison of the proinflammatory cytokines produced by the DC line stimulated with live commensal bacteria between aerobic and anaerobic conditions. The DC line was stimulated with live commensal bacteria under aerobic (white bar) or anaerobic (black bar) conditions for 4 h. Thereafter, the DC line was cultured for an additional 20 h (total of 24 h) under aerobic culture conditions. IL-6, IL-8, or TNF-α production by the DC line represents the results of three independent experiments. The commensal bacteria used in this study are as follows: Fusobacterium varium (F. varium), Fusobacterium nucleatum (F. nucleatum), Bacteroides vulgatus (B. vulgatus), Clostridium clostridioforme (C. clostridioforme), and Escherichia coli (E. coli). A t test was used to compare the levels of proinflammatory cytokines produced by the DC line stimulated with commensal bacteria under aerobic or anaerobic stimulation conditions. *p < 0.05, **p < 0.01, and ***p < 0.001.
