Figure 2

Schematic mapping of the mutations in the SARS-CoV-2 whole genome. The full-length (29,903 bp) SARS-CoV-2 Betacoronavirus RNA genome consists of an ORF1a encoding 10 nonstructural proteins (nsp1–10) and an ORF1b encoding 16 nonstructural proteins (nsp1–16) in the 5´ untranslated region (UTR). The structural proteins correspond to 4 genes in the 3′ UTR: spike (S), envelope (E), membrane protein (M), and nucleocapsid (N) genes. The mutations and changes in amino acid residues (with position numbers) have been individually presented in the diagram.