Figure 6 | Scientific Reports

Figure 6

From: Human chorion-derived mesenchymal stem cells suppress JAK2/STAT3 signaling and induce apoptosis of cholangiocarcinoma cell lines

Figure 6

CH-CM suppresses JAK2/STAT3 signaling in CCA cell lines. CCA cell lines were cultured with CH-CM at 0%, 50%, and 75% for 8 h. (A) Western blot analysis showed that CH-CM decreases the expression of total and phosphorylated form of JAK2 and STAT3. (B) The relative expression analysis showed a dose-dependent manner and significant inhibition on the JAK2/STAT3 signaling in CCA cell lines (p < 0.001). Full length western blots are provided in Supplementary Fig. 5.

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