Table 1 Clinical characteristics of the study cohort.
From: Differentially methylated and expressed genes in familial type 1 diabetes
Family | Members | Symbol | Phenotype | Age at recruitment (years) | Age at onset of T1D (years) |
|---|---|---|---|---|---|
A | Father | I_1_A | healthy | 46 | – |
Mother | I_2_A | healthy | 34 | – | |
Daughter | II_1_A | healthy | 14 | – | |
Son | II_2_A | T1D | 7 | 5 | |
Daughter * | II_3_A | T1D | 12 | 6 | |
Daughter * | II_4_A | T1D | 12 | 6 | |
B | Mother | I_1_B | healthy | 37 | – |
Father | I_2_B | T1D | 39 | 12 | |
Daughter | II_1_B | healthy | 6 | – | |
Son | II_2_B | healthy | 9 | – | |
Daughter | II_3_B | T1D | 13 | 11 | |
Daughter †| II_4_B | T1D | 11 | 10 | |
Daughter †| II_5_B | T1D | 11 | 10 | |
C | Father | I_1_C | healthy | 43 | – |
Mother | I_2_C | healthy | 42 | – | |
Son | II_1_C | T1D | 9 | 2 | |
Daughter | II_2_C | T1D | 14 | 1 |
