Table 3 Effect of MEZZR on cell growth inhibition, survival time and body weight gain of EAC cell-bearing Swiss albino mice.

From: Antioxidant, cytotoxic and apoptotic activities of the rhizome of Zingiber zerumbet Linn. in Ehrlich ascites carcinoma bearing Swiss albino mice

Treatment

Viable EAC cells on day 6 after inoculation (× 107 cells/ml)

Percentage (%) cell growth inhibition

Mean survival time; MST

(in days)

Percentage increase of life span;

% ILS

Body weight gain (g) after 15 days

EAC + Control

5.91 ± 0.19

–

23.8 ± 1.30

–

14.80 ± 0.83

EAC + MEZZR (10 mg/kg)

2.44 ± 0.28*

58.87 ± 4.16

28.6 ± 2.07*

20.23 ± 3.79

6.7 ± 0.24*

EAC + MEZZR (20 mg/kg)

2.22 ± 0.26*

69.64 ± 2.58

36.40 ± 1.14*

53.40 ± 4.07

3.28 ± 0.32*

EAC + Bleomycin (0.3 mg/kg)

0.39 ± 0.09*

92.84 ± 1.68

39.5 ± 0.98*

83.72 ± 3.45

2.7 ± 0.65*

  1. Data are expressed as mean ± SD for six animals in each group. Bleomycin is an anticancer drug. *P < 0.05: against EAC control group.
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