Table 7 Optimization of 1, 9 and 15 on EGFR and UCH-1 and UCH-2 chordoma cells lines.

From: Optimization of the 4-anilinoquin(az)oline scaffold as epidermal growth factor receptor (EGFR) inhibitors for chordoma utilizing a toxicology profiling assay platform

  1. aAbbreviations for columns from left to right. CM: Cell morphology; CMI: Cell membrane integrity; ROS: Reactive superoxide species; GSH: Glutathione; NMI1: Nuclear membrane integrity 1; CC: Cell Cycle; NMI2: Nuclear membrane integrity 2; MMP: Mitochondrial membrane depolarization; CHI: Cell Health Index. ball n = 2.
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