Figure 1 | Scientific Reports

Figure 1

From: Hypo-osmotic stress induces the epithelial alarmin IL-33 in the colonic barrier of ulcerative colitis

Figure 1

IL-33 in acute ulcerative colitis (AUC). Image (A-F) show formalin-fixed, paraffin-embedded colonic biopsies stained for IL-33 (brown) and nuclei stained with hematoxylin (blue). Arrows point to inflammatory cells infiltrating the epithelium. Scales bars = 50 μm. Image (G) shows dual staining of AUC with IL-33 (red) and endothelial vessels marked by CD34 (green). White frame in image (G) is enlarged as image (H). Scale bars = 50 μm. The graph to the far right (I) shows positive IL-33 cells per 1000 cells quantified by Qupath analysis software into epithelial and stromal compartments. Asterisk: 327 positive cells/1000 cells.

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