Table 1 Clinical background of RM patients and AA controls for genome-wide DNA methylation analysis and pyrosequencing.
From: Characteristic DNA methylation profiles of chorionic villi in recurrent miscarriage
Genome-wide analysis | Pyrosequencing analysis* | |||||
|---|---|---|---|---|---|---|
RM Patients (n = 5) | AA Controls (n = 5) | P value | RM Patients (n = 19) | AA Controls (n = 19) | P value | |
Age | 34.8 ± 3.1 | 32.6 ± 7.7 | 0.62 | 34.5 ± 3.6 | 32.4 ± 6.2 | 0.23 |
Gestational weeks | 7.2 ± 0.8 | 7.1 ± 0.8 | 0.80 | 7.0 ± 1.0 | 7.8 ± 1.3 | 0.053 |
Miscarriages | 4.8 (3–7) | 0 (0) | < 0.01 | 3.7 (3–7) | 0.32 (0–3) | < 0.01 |
Previous live births | 0.2 (0–1) | 2.0 (0–5) | 0.13 | 0.42 (0–1) | 1.6 (0–5) | < 0.01 |
Male/female ratio of POC | 4:1 | 1:4 | < 0.01 | 10:9 | 8:9 not tested:2 | 0.48 |
