Table 1 Muscle and liver enzyme activity, fatty acid transport protein mRNA expression, and PPAR mRNA expression in yellow-rumped warblers maintained on a diet with 0.0 ppm (control) or 0.5 ppm (exposed) methylmercury for 14 d. Enzyme activity (μmol min−1 g−1) and expression (− ΔCT) values are means ± SE, and test statistics are from final general linear models.
From: Short-term mercury exposure disrupts muscular and hepatic lipid metabolism in a migrant songbird
Control | Exposed | t | df | P | |
---|---|---|---|---|---|
Muscle | |||||
CS | 214.1 ± 11.9 | 182.5 ± 12.8 | − 1.807 | 1, 23 | 0.085 |
CPT | 7.7 ± 0.7 | 6.0 ± 0.5 | − 2.28 | 3, 20 | 0.034 |
LDH | 691.1 ± 76.7 | 586.9 ± 57.8 | − 1.17 | 1, 23 | 0.26 |
FAT/CD36 | − 3.4 ± 0.3 | − 3.5 ± 0.3 | 0.34 | 4, 15 | 0.74 |
FABPpm | − 2.2 ± 0.3 | − 2.1 ± 0.3 | − 0.44 | 3, 21 | 0.67 |
H-FABP | − 1.0 ± 0.3 | − 0.8 ± 0.3 | 0.77 | 4, 20 | 0.45 |
PPAR-α | − 7.5 ± 0.8 | − 8.0 ± 0.8 | 0.24 | 3, 21 | 0.82 |
PPAR-ß | − 5.5 ± 0.6 | − 4.3 ± 0.5 | − 1.51 | 2, 22 | 0.15 |
PPAR-γ | − 10.7 ± 0.8 | − 11.1 ± 0.7 | 0.42 | 3, 21 | 0.68 |
Liver | |||||
CS | 82.3 ± 7.6 | 107.0 ± 8.0 | 2.25 | 2, 22 | 0.035 |
CPT | 10.8 ± 0.6 | 11.0 ± 0.7 | 0.17 | 2, 22 | 0.87 |
LDH | 1214.1 ± 176.4 | 1096.2 ± 92.4 | − 0.23 | 2, 22 | 0.82 |
FAT/CD36 | − 4.1 ± 0.2 | − 4.6 ± 0.2 | 2.16 | 3, 18 | 0.045 |
FABPpm | − 0.2 ± 0.2 | − 0.5 ± 0.2 | 2.93 | 4, 18 | 0.009 |
PPAR-α | − 4.6 ± 0.5 | − 5.0 ± 0.7 | 0.39 | 3, 19 | 0.71 |
PPAR-ß | − 6.3 ± 0.7 | − 5.1 ± 0.5 | − 1.39 | 2, 20 | 0.18 |
PPAR-γ | − 9.5 ± 0.3 | − 10.1 ± 0.3 | 2.33 | 4, 17 | 0.033 |