Figure 4 | Scientific Reports

Figure 4

From: The optimized jugular vein catheterization reinforced cocaine self-administration addictive model for adult male Sprague–Dawley rats

Figure 4

Self-administration training for rats. (A) Self-administration apparatus. (B, C) The comparison before and after valid nose-poke for experimental rat. Before valid nose-poke, only green light is on (B). When the experimental rats finish a valid nose-poke, the system pumps the drug once (T = 1.25 s, ν = 1.60 mL/min), which accompanies a series of changes in environmental cues such as signal lights (a green light turning off and a red light turning on for 20 s), a valid nose-poke light (T = 20 s), and a sound (buzzer, T = 1.25 s) (C). (D) The original recording of experimental rat’s behavioral events.

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