Figure 5 | Scientific Reports

Figure 5

From: Mouse oocytes carrying metacentric Robertsonian chromosomes have fewer crossover sites and higher aneuploidy rates than oocytes carrying acrocentric chromosomes alone

Figure 5

Aneuploidy in MII-oocytes ovulated by RbT-carrier and WT females. (a) The average number of ovulated oocytes by WT, Rb5, and RBF young (3–4 months) or old (6–9 months) females. The total number of examined mice is given on the top of each column. *Significant difference at P < 0.05 by Mann–Whitney test. (b) Representative images of nondisjunction (NDJ) and precocious separation of sister chromatids (PSSC) aneuploidy. White circle with broken line indicates a single chromatid (Cht) as the PSSC type aneuploidy. Arrowhead indicates an RbT chromosome. Scale bar 10 µm. (c) The rate of NDJ and PSSC aneuploidy in the oocytes from young vs. old females as shown in (a). The total number of examined oocytes is given on the top of each column. *Significant difference at P < 0.05 by χ2-test.

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