Table 2 Incidence of early-onset vasomotor symptoms by AMH quintiles in premenopausal women (n = 2041).

From: Low anti-Müllerian hormone levels are associated with an increased risk of incident early-onset vasomotor symptoms among premenopausal women

AMH level

Person-years (PY)

No of incident early-onset VMS

Incidence rate

(cases per 100 PY)

Age-adjusted

HR (95% CI)

Multivariable-adjusted HR (95% CI)

Quintile 5

1862.5

105

5.6

Reference

Reference

Quintile 4

1911.8

118

6.2

1.06 (0.82–1.39)

1.02(0.78–1.33)

Quintile 3

1845.8

145

7.9

1.40 (1.08–1.80)

1.37(1.06–1.76)

Quintile 2

1729.0

145

8.4

1.41(1.09–1.83)

1.36(1.04–1.76)

Quintile 1

1467.1

195

13.3

2.43(1.88–3.13)

2.38(1.84–3.08)

P for trend

   

 < .001

 < .001

AMH as a continuous variable

8816.2

708

8.0

1.29 (1.17–1.42)

1.28 (1.16–1.41)

  1. Parametric proportional hazard models were used to estimate the hazard ratios with 95% confidence intervals. The multivariable model was adjusted for age, education level, parity, physical activity, smoking status, alcohol intake, hypertension, lipid lowering agent and body mass index.
  2. Abbreviation: AMH, anti-Müllerian hormone; CI, confidence interval; HR, hazard ratio.
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