Figure 1

Heatmap of top 10 down and upregulated sepsis-specific DEGs in (A) elder (GSE67652), (B) adult (GSE67652), and (C) children (GSE80496) age groups. The expression of DEGs (within rows) is normalized across all the samples (within columns). The cluster dendrograms indicating hierarchical clustering (Euclidean distance-based) for both columns and rows are exhibited along the top and left sides of the plot. The gender type annotation bar (only for children age groups) and sample type annotation bar (for all age groups) are placed at the top of heatmaps. The position of genes on their respective chromosome number is shown as a vertical annotation bar (multicolor bands) in the right panel.