Table 1 Maternal and neonatal characteristics.

From: Neonatal outcomes in women with preterm premature rupture of membranes at periviable gestational age

Characteristics

GW at PPROM

p value

Total (17–33)

N = 94

Group 1 (17–23)

N = 24

Group 2 (24–27)

N = 27

Group 3 (28–33)

N = 43

Maternal characteristics

Maternal age (year)

28.4 ± 5.4 (20–41)

29 ± 5 (22–41)

28.2 ± 5 (21–41)

28.2 ± 5.8 (20–41)

0.401

Gravidity

4.8 ± 3.2 (1–16)

4.8 ± 2.8 (1–12)

4 ± 2.2 (1–9)

5.1 ± 3.8 (1–16)

0.826

Parity

3 ± 2.4 (0–12)

3 ± 2.2 (0–8)

2.5 ± 1.9 (0–7)

3 ± 2.8 (0–12)

0.493

Celeston (2 courses)

93 (98.9)

23 (95.8)

27 (100)

43 (100)

0.229

Magnesium treatment

92 (97.9)

22 (91.7)

27 (100)

43 (100)

0.051

Treatment with antibiotics (mercer protocol)

93 (98.9)

24 (100)

26 (96.3)

43 (100)

0.285

Chorioamnionitis

18 (19.1)

4 (16.7)

11 (40.7)

3 (7)

0.002

Previous preterm delivery*

12 (12.8)

7 (29.2)

0

5 (11.6)

0.024

Placenta abruption

22 (23.4)

9 (37.5)

7 (25.9)

6 (14)

0.086

GW at onset of PPROM (median, week)

27 ± 4.2

22 ± 1.6

26 ± 1.2

31 ± 1.4

 < 0.001

Latency period (median, day)

16 ± 21.8 (7–105)

49 ± 28.1 (12–105)

17 ± 14.8 (7–61)

12 ± 5.7 (7–26)

 < 0.001

Cesarean delivery

45 (47.9)

17 (70.8)

14 (51.9)

14 (32.6)

0.01

Neonatal characteristics

GA at delivery (week)

30.8 ± 3.1 (23–34)

28.5 ± 3.3 (23–34)

29.3 ± 2.4 (25–34)

33 ± 1.3 (30–34)

 < 0.001

Male gender

60 (63.8)

14 (58.3)

20 (74.1)

26 (60.5)

0.416

Birth weight (g)

1615.1 ± 544.4 (488–2945)

1270.6 ± 472.1 (488–2120)

1347.7 ± 410.3 (730–2270)

1975 ± 428.4 (1145–2945)

 < 0.001

Apgar score 1 min

6.8 ± 2.5 (1–9)

5.1 ± 2.4 (1–9)

6.2 ± 2.8 (1–9)

8.1 ± 1.6 (2–9)

 < 0.001

Apgar score 5 min

9.6 ± 1.8 (3–10)

7.6 ± 1.4 (4–10)

8.3 ± 1.9 (4–10)

9.4 ± 1.3 (3–10)

 < 0.001

Survived to Hospital discharge

86 (91.5)

19 (79.2)

24 (88.9)

43 (100)

0.012

  1. Data are expressed as mean/median ± standard deviation (range) or n (%).
  2. GA gestational age, GW gestational week.
  3. *2 missing values.
  4. Significant values are in bold.