Table 1 Patients with B-ALL general information.
From: Proteomic profiling of plasma exosomes from patients with B-cell acute lymphoblastic leukemia
Sample | Age/Sex | Type | Clinical status | Primary cytogenetic abnormality | Mutation | Fusion gene | Blasts (%) | Differentiation antigen expression |
|---|---|---|---|---|---|---|---|---|
1 | 26/F | Plasm | ND | JAK2, EPPK1, PDE4DIP, FOXP1 | ETV6-NTRK3 | 76% | CD34, CD10, CD19, CD22, HLA-DR, CD38 | |
2 | 21/F | Plasm | ND | KMT2C, BCL11B, FANCD2 | KMT2A-AFF1 | 77% | CD34, CD19, CD22, HLA-DR | |
3 | 35/M | Plasm | ND | DDX41, PMS2, ERCC6L2, SLX4 | Missing | 94.5% | CD34, CD10, HLA-DR, CD19, CD22, CD20, CD38 | |
4 | 47/F | Plasm | ND | 45, XX, der(3;7)(q10;q10),t(9;22)(q34;q11.2)3/45,idem,ā+ā1, dic(1;17)(p13;p11)2/46,XX15 | BRCA2, EFL1, ACD | BCR-ABL1 | 86% | CD34, CD10, CD19, HLA-DR, CD13 |
5 | 35/F | Plasm | ND | 46, XX5 | EPAS1, ZNF479, BCLF1 | BCR-ABL1 | 43% | CD34, CD10, CD19, HLA-DR, CD22 |
6 | 19/M | Plasm | ND | 45, XY,āāā3, add(7)(p11),āāā9, del(22)(q11),ā+āmar12/46, XY6 | CTNND2, CHD4, NUP214, EPPK1, NCOR1, BRCA2 | Missing | 98% | CD34, CD10, CD19, CD22, HLA-DR, CD38 |
7 | 46/F | Plasm | ND | RUNX1, BCR, IDH1, ARID4A, RAD50 | BCR-ABL1 | 88% | CD10, CD19, CD38, CD20, CD13, CD33 | |
8 | 25/M | Plasm | ND | 46, XY8 | HGF, PDE4DIP, TRIP11 | Missing | 81% | CD34, CD10, CD19, CD22, HLA-DR, CD20, CD38, CD13 |
9 | 32/M | Plasm | ND | 47, XY,ā+āX, t(4;11)(q21;q23),āāā17,ā+ār17/46, XY3 | TP53, FANCD2 | KMT2A-AFF1 | 82.5% | CD34, CD19, CD22, HLA-DR, CD38 |
10 | 45/F | Plasm | ND | 46, XX, t(9; 22)(q34; q11.2)20 | PHF6, FAM47C, ARID1B, SUFU | BCR-ABL1 | 87% | CD34, CD10, CD19, CD22, CD38, HLA-DR, CD20 |
11 | 48/M | Plasm | ND | 46, XY17 | TP53, CCND3, ID3, MYC, TP63 | Missing | 88.5% | CD10, CD19, HLA-DR, CD22, CD20, CD38 |
12 | 36/M | Plasm | ND | 46, XY20 | PTEN, MYC, EPPK1, BRINP3 | Missing | 81% | CD34, CD10, CD19, HLA-DR, CD38 |
13 | 45/M | Plasm | ND | Missing | PTEN, RPL22, PRB2, TAF1 | Missing | 97% | CD34, CD10, CD19, HLA-DR |
14 | 34/F | Plasm | ND | 46, XX14 | Missing | Missing | 66% | CD34, CD10, CD19, CD79a, TDT, HLA-DR |
15 | 47/M | Plasm | ND | GRIN2A, SLX4, AXIN1, PCLO, CDH11 | BCR-ABL1 | 72.5% | CD34, CD10, CD19, CD22, HLA-DR | |
16 | 34/F | Plasm | ND | 46, XX20 | TP53, EPPK1, FBLN2, MYD88, IRF4, AURKA | Missing | 79% | CD10, CD19, CD22, CD20, CD38, HLA-DR |
17 | 49/M | Plasm | ND | 46, XY, t(9; 22)(q34; q11.2)16 | FOXP2, AMER1, BCR, PDE4DIP, CDC73 | BCR-ABL1 | 89.1% | CD34, CD10, CD19, CD38, HLA-DR |
18 | 55/M | Plasm | ND | 46, XY, t(9; 22)(q34; q11)15/47,idem,ā+āder(22)t(9; 22)1/48, idem,ā+ā8,ā+ā?131/46, XY3 | ASXL1, EPHA3, BCR | BCR-ABL1 | 78% | CD34, CD10, CD19, CD22, HLA-DR |
