Table 3 Assessing the certainty of the evidence presented for each outcome.
No. of studies | Study design | Risk of bias | Inconsistency | Indirect evidence | Imprecision | Other considerations | Therapeutic exercise | Placebo | Absolute (95% CI) | Certainty |
---|---|---|---|---|---|---|---|---|---|---|
Independent gait: three steps without assistance. Treadmill-type aerobic Therapeutic exercise vs. control (assessed: days-to-event) | ||||||||||
3 | Randomized trials | Very serious a | Not serious b | Not serious | Serious b | No effect was observed | 41 | 41 | MD 46.79 days less (32.6 lower than 126.19 higher.) | ⨁⨁◯◯ LOW |
Motor development (mental dimension) intervention: neuromuscular exercise vs control (regular interventions) (assessed: Gross motor function measure) | ||||||||||
1 | Randomized trials | Not serious | – | Serious c | Serious b | No effect was observed | 10 | 10 | MD 5.28 less (14.07 less than 3.51 higher.) | ⨁⨁◯◯ LOW |
Motor development (motor dimension): intervention: neuromuscular exercise vs control (regular interventions) (assessed: Gross motor function measure) | ||||||||||
1 | Randomized trials | Not serious | – | Serious c | Serious b | No effect was observed | 10 | 10 | MD 5.54 less (18.01 less than 6.93 higher.) | ⨁⨁◯◯ LOW |
Gait speed follow-up 4 and 6 weeks intervention: aerobic exercise-weight-supported treadmill training vs regular intervention | ||||||||||
1 | Randomized trials | Serious d | – | Not serious | Serious b | No effect was observed | 12 | 12 | MD 0.1 higher (-0.02 lower than 0.21 higher.) | ⨁⨁◯◯ LOW |
Motor development follow-up 4 and 6 weeks intervention: aerobic exercise-weight-supported treadmill training vs regular intervention (assessed with: GMFM) | ||||||||||
1 | Randomized trials | Serious d | – | Not serious | Not serious b | No effect was observed | 12 | 12 | MD 2.07 higher (0.28 higher than 3.86 higher.) | ⨁⨁⨁◯ MODERATE |