Figure 3
From: Evidence for correlations between BMI-associated SNPs and circRNAs
Consideration of the linkage disequilibrium of BMI-SNPs located on circRNA genomic loci. (a) To correct for the LD of SNPs, we have defined non-significant SNPs (black; total of 1,518,661 SNPs) that were located within a 1 Mb region adjacent to a significant SNP (P < 5 × 10−8) as a ‘significant region’ (grey; total of 805,908 SNPs) as well. (b) Further, in an additional LD approximation, non-significant variants (black; total of 2,247,465 SNPs) located within an already described region of high LD (as stated in plinkQC70) were classified as ‘significant’ (grey; total of 77,104 SNPs). The corresponding statistical results can be obtained from Supplementary Table S7. ****P < 0.0001; SNP single nucleotide polymorphism.
