Figure 2

The resonance process of SARS-CoV-2 and its microwave absorption spectra for different concentrations compared with HCoV-229E under different experimental conditions. (A) Schematic illustrating the displacement of two dipolar modes of the spherical particle, with angular momentum l = 1 and with quantum numbers n = 0 or 1, driven by the electric field generated by the microwave. The blue and green arrows represent the displacements of the shells and the core respectively. Under the viewpoint of two-body problem, for the vibration mode of n = 0, the motion of the virion is like an inner cylinder and an outer ring that are moving in opposite directions. For the other vibration mode of n = 1, the motion behaves like a core and a shell that are moving in opposite directions. (B) Normalized insertion loss for different concentrations of SARS-CoV-2 (107 PFU/mL, black-colored line; 106 PFU/mL, purple-colored line; and 105 PFU/mL, blue-colored line) purified in DMEM. Every spectrum in the figure represents one measurement of the normalized IL. (C) The normalized insertion loss of SARS-CoV-2 (black-colored line) and HCoV-229E (green-colored line) with the same viral concentration (107 PFU/mL) and purified in the same medium DMEM (pH 7.4). The dataset of SARS-CoV-2 in this plot is the same as (B) for the comparison. (D) The normalized insertion loss of HCoV-229E in DMEM with different acidity levels. (green-colored line: pH 7, 107 PFU/mL; red-colored line: pH 6, 0.9 × 107 PFU/mL) The dataset of HCoV-229E in neutral medium in this plot is the same as (C) for the comparison.