Table 2 Summary of cytokine measurements in CSF.
From: Cytokine changes in cerebrospinal fluid following vascular surgery on the thoracic aorta
Cytokine | Timepoint | CSF Median [IQR] (pg/mL) | Adjusted-p value Wilcoxon Signed-Rank Test between T1 and T2 | Average fold change |
---|---|---|---|---|
IL-1β | T1 T2 | 0.14 [0.14–0.15] 0.60 [0.36–0.84] | < 0.01 | 5.4 |
IL-2 | T1 T2 | 0.20 [0.20–0.23] 0.30 [0.21–0.81] | < 0.05 | 4.6 |
IL-4 | T1 T2 | 0.02 [0.01–0.03] 0.03 [0.01–0.08] | ns | 4.5 |
IL-6 | T1 T2 | 0.98 [0.39–1.28] 15.91 [9.73–62.57] | < 0.01 | 63.3 |
IL-8 | T1 T2 | 26.85 [9.35–42.32] 919.23 [333.42–1366.63] | < 0.01 | 31.0 |
IL-10 | T1 T2 | 0.30 [0.19–0.43] 0.85 [0.37–1.00] | < 0.05 | 4.5 |
IL-12p70 | T1 T2 | 0.09 [0.08–0.17] 0.11 [0.08–0.12] | ns | 2.8 |
IL-13 | T1 T2 | 1.14 [0.55–1.86] 2.78 [1.67–12.75] | < 0.01 | 5.2 |
IFN-γ | T1 T2 | 0.605 [0.54–0.67] 0.605 [0.54–0.63] | ns | 2.6 |
TNF-α | T1 T2 | 0.52 [0.32–0.96] 0.99 [0.51–2.10] | ns | 3.9 |