Table 2 Summary of cytokine measurements in CSF.

From: Cytokine changes in cerebrospinal fluid following vascular surgery on the thoracic aorta

Cytokine

Timepoint

CSF Median [IQR]

(pg/mL)

Adjusted-p value Wilcoxon Signed-Rank Test between T1 and T2

Average fold change

IL-1β

T1

T2

0.14 [0.14–0.15]

0.60 [0.36–0.84]

 < 0.01

5.4

IL-2

T1

T2

0.20 [0.20–0.23]

0.30 [0.21–0.81]

 < 0.05

4.6

IL-4

T1

T2

0.02 [0.01–0.03]

0.03 [0.01–0.08]

ns

4.5

IL-6

T1

T2

0.98 [0.39–1.28]

15.91 [9.73–62.57]

 < 0.01

63.3

IL-8

T1

T2

26.85 [9.35–42.32]

919.23 [333.42–1366.63]

 < 0.01

31.0

IL-10

T1

T2

0.30 [0.19–0.43]

0.85 [0.37–1.00]

 < 0.05

4.5

IL-12p70

T1

T2

0.09 [0.08–0.17]

0.11 [0.08–0.12]

ns

2.8

IL-13

T1

T2

1.14 [0.55–1.86]

2.78 [1.67–12.75]

 < 0.01

5.2

IFN-γ

T1

T2

0.605 [0.54–0.67]

0.605 [0.54–0.63]

ns

2.6

TNF-α

T1

T2

0.52 [0.32–0.96]

0.99 [0.51–2.10]

ns

3.9

  1. Cytokine levels in cerebrospinal fluid (CSF) before surgery (T1) and the day after surgery (T2), ns = non-significant.