Table 1 Characteristics of study participants at baseline.
Placebo (n = 60) | Inosine (n = 60) | |
---|---|---|
Age (years) | 68.8 (1.9) | 68.2 (2.3) |
Ethnicity, n (%) | ||
NZ European | 59 (98%) | 58 (97%) |
NZ Māori | 1 (2%) | 0 |
NZ Asian | 0 | 2 (3%) |
Serum urate | ||
mmol/L | 0.28 (0.06) | 0.27 (0.06) |
mg/dL | 4.7 (1.0) | 4.5 (1.0) |
Weight (kg) | 72.4 (12.6) | 67.5 (10.9) |
Body mass index (kg/m2) | 27.3 (4.7) | 26.1 (4.2) |
Waist circumference (cm) | 89 (12) | 85 (11) |
Systolic blood pressure (mmHg) | 136 (17) | 134 (18) |
Diastolic blood pressure (mmHg) | 73 (8) | 72 (10) |
LDL cholesterol (mmol/L) | 3.0 (0.9) | 3.2 (0.8) |
HDL cholesterol (mmol/L) | 1.8 (0.4) | 1.9 (0.5) |
Triglycerides (mmol/L) | 1.0 (0.4) | 1.0 (0.4) |
C-reactive protein (mg/L) | 2.3 (2.5) | 2.0 (1.9) |
Fasting glucose (mmol/L) | 5.0 (0.5) | 4.9 (0.4) |
HbA1c (mmol/mol) | 37 (3) | 36 (3) |
Insulin (mU/L) | 8.7 (4.1) | 7.8 (3.4) |
FEUA (%) | 8.0 (3.1) | 8.0 (2.7) |
Creatinine (µmol/L) | 63.3 (8.6) | 62.5 (8.7) |
eGFR (mL/min/1.73 m2) | 91 (15) | 92 (14) |