Figure 1

Effects of dietary regimens on body weight, composition and glucose tolerance at pre-tumour endpoint. (a) Experimental timeline showing duration of diets and analysis endpoints, (b) Body weight, (c) Fat mass, (d) Lean mass, (e) Fat mass (% body weight), (f) Lean mass (% body weight), (g) Fasting blood glucose levels, (h) Glucose clearance over time, (i) Fasting insulin levels, (j) HOMA-IR scores. Error bars SEM, (b–f) data n = 22–23/group, (g–k) data n = 10/group, ns p > 0.05, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, ordinary one-way ANOVA with Tukey’s multiple comparisons test.