Table 1 Comparison of clinic-pathological factors and outcomes between N-HEN and control groups.
N-HEN | CG | P value | |||
|---|---|---|---|---|---|
n = 24 | n = 22 | ||||
Gender | |||||
Male | 16 | 67% | 15 | 68% | |
Female | 8 | 33% | 7 | 32% | 0.8737 |
Age (years, median ± SD) | 71.0 | ± 13.1 | 68.1 | ± 13.0 | 0.1055 |
Body mass index (kg/m2, median ± SD) | 21.3 | ± 2.9 | 22.2 | ± 2.8 | 0.1152 |
pT stage | |||||
T1 | 2 | 8% | 9 | 41% | |
T2 | 2 | 8% | 1 | 5% | |
T3 | 7 | 30% | 4 | 18% | |
T4 | 13 | 54% | 8 | 36% | 0.2128 |
pN stage | |||||
N0 | 7 | 33% | 12 | 55% | |
N1 | 1 | 5% | 5 | 23% | |
N2 | 3 | 14% | 2 | 9% | |
N3 | 10 | 48% | 3 | 14% | 0.1652 |
pStage | |||||
I | 4 | 17% | 8 | 36% | |
II | 4 | 17% | 7 | 32% | |
III | 16 | 66% | 7 | 32% | 0.1549 |
Approach | |||||
Open | 5 | 21% | 13 | 62% | |
Laparoscopic/Robotic | 19 | 79% | 8 | 38% | 0.0123 |
Posoperative complication (Clavien-Dindo ≥ 3) | 1 | 4% | 1 | 5% | 1.0000 |
Anastomotic leakage | 1 | 1 | |||
Others | 0 | 0 | |||
Postoperative hospital stay (days, mean ± SD) | 15.9 | ± 6.7 | 22.5 | ± 32.0 | 0.1394 |
Completion rate of adjuvant chemotherapy in Stage II–III patients | 14/20 | 70% | 4/14 | 29% | 0.0420 |
Postoperative days until adjuvant chemotherarpy (days) | 36.6 | ± 16.2 | 38.9 | ± 9.6 | 0.3514 |
Duration of adjuvant chemotherapy (days) | 458.0 | ± 278.9 | 261.7 | ± 157.7 | 0.0313 |
Status at 3 months (mean ± SD) | |||||
Body weight loss (%) | 4.0 | ± 6.3 | 15.2 | ± 7.1 | < 0.0001 |
Pre-albuminn (mg/dl) | 24.1 | ± 4.3 | 14.7 | ± 4.1 | < 0.0001 |
Albumin (mg/dl) | 3.8 | ± 0.3 | 3.6 | ± 0.8 | 0.0985 |
Total protein (g/dl) | 6.7 | ± 0.4 | 6.2 | ± 0.8 | 0.0066 |
Total cholesterol (mg/dl) | 154.3 | ± 25.9 | 153.6 | ± 45.7 | 0.4854 |
Hemiglobin (g/dl) | 11.8 | ± 1.4 | 11.1 | ± 1.6 | 0.0506 |
Status at 6 months (mean ± SD) | |||||
Body weight loss (%) | 7.7 | ± 6.5 | 17.8 | ± 7.2 | < 0.0001 |
Pre-albuminn (mg/dl) | 22.1 | ± 5.3 | 16.2 | ± 5.6 | 0.0037 |
Albumin (mg/dl) | 3.8 | ± 0.4 | 3.6 | ± 0.6 | 0.1319 |
Total protein (g/dl) | 6.7 | ± 0.5 | 6.4 | ± 0.7 | 0.0550 |
Total cholesterol (mg/dl) | 177.9 | ± 31.4 | 164.5 | ± 21.3 | 0.1182 |
Hemiglobin (g/dl) | 11.9 | ± 1.4 | 11.2 | ± 1.4 | 0.0550 |
