Table 4 Multivariate analysis for in-hospital mortality and clinical worsening.

From: Ability of IMPROVE and IMPROVE-DD scores to predict outcomes in patients with severe COVID-19: a prospective observational study

 

Mortality (n = 38)

Clinical worsening (n = 56)

Odd ratio (95% CI)

P value

Odd ratio (95% CI)

P value

SpO2 (%)

0.85 (0.76–0.96)

0.010

0.84 (0.76–0.92)

< 0.001

APACHE II

1.03 (0.85–1.26)

0.766

1.14 (0.96–1.35)

0.142

Charlson comorbidity index

1.27 (0.69–2.34)

0.443

1.50 (0.90–2.41)

0.128

IMPROVE-DD

7.48 (2.36–23.66)

0.001

1.56 (1.09–2.23)

0.015

CRP (mg/dL)

1.01 (1.00–1.02)

0.208

1.01 (1.00–1.02)

0.063

  1. APACHE II acute physiology and chronic health evaluation II, CI confidence interval, CRP C-reactive protein, DD D-dimer, IMPROVE international medical prevention registry on venous thromboembolism, SpO2 peripheral oxygen saturation.
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