Table 2 Risk of GG ≥ 2 and GG ≥ 3 relative to the low-risk group (PRS < 25th percentile).

From: Polygenic risk score for tumor aggressiveness and early-onset prostate cancer in Asians

Groups by percentile

Risk of GG ≥ 2

Risk of GG ≥ 3

HR

95% CI

p-value

HR

95% CI

p-value

 ≥ 75

4.649

3.544–6.098

 < 0.001

2.026

1.678–2.446

 < 0.001

50–75

3.008

2.364–3.827

 < 0.001

1.708

1.419–2.057

0.001

25–50

2.105

1.685–2.629

 < 0.001

1.392

1.158–1.673

 < 0.001

 < 25

Reference

–

–

Reference

–

–

  1. GG grade group, HR hazard ratio, CI confidence interval.
Back to article page