Table 4 Effect size of central obesity on incident diabetes in prespecified and exploratory subgroups.
Characteristic | No of participants | HR (95%CI) | P value | P for interaction |
|---|---|---|---|---|
Gender | 0.9171 | |||
Male | 1240 | 2.12 (1.09, 4.13) | 0.0269 | |
Female | 486 | 3.15 (0.27, 36.24) | 0.3568 | |
BMI | 0.7981 | |||
< 25 kg/m2 | 1946 | 1.59 (0.89, 2.84) | 0.1202 | |
≥ 25 kg/m2 | 502 | 1.44 (0.61, 3.39) | 0.4017 | |
Age | 0.3739 | |||
< 50 | 1238 | 1.68 (0.84, 3.37) | 0.1453 | |
≥ 50 | 518 | 0.87 (0.25, 2.95) | 0.8181 | |
FPG (mg/dL) | 0.9958 | |||
Low | 802 | 1.02 (0.06, 16.79) | 0.9882 | |
High | 874 | 1.77 (0.91, 3.43) | 0.0911 | |
HbA1c (%) | 0.4800 | |||
Low | 634 | 0.88 (0.22, 3.53) | 0.8577 | |
High | 1046 | 1.61 (0.88, 2.93) | 0.1216 | |
TC (mg/dL) | 0.6490 | |||
Low | 818 | 1.57 (0.56, 4.46) | 0.3927 | |
High | 840 | 1.23 (0.50, 3.05) | 0.6530 | |
TG (mg/dL) | 0.3787 | |||
Low | 798 | 2.89 (0.70, 12.02) | 0.1441 | |
High | 828 | 1.54 (0.77, 3.07) | 0.2241 | |
HDL-C (mg/dL) | 0.3523 | |||
Low | 804 | 1.41 (0.70, 2.84) | 0.3359 | |
High | 818 | 0.68 (0.18, 2.56) | 0.5665 | |
ALT (U/L) | 0.5674 | |||
Low | 700 | 2.77 (0.59, 12.90) | 0.1955 | |
High | 964 | 1.81 (0.96, 3.42) | 0.0678 | |
AST (U/L) | 0.9342 | |||
Low | 676 | 1.07 (0.22, 5.13) | 0.9330 | |
High | 1012 | 1.20 (0.60, 2.40) | 0.5972 | |
GGT (U/L) | 0.1643 | |||
Low | 776 | 0.82 (0.16, 4.31) | 0.8126 | |
High | 896 | 3.10 (1.35, 7.12) | 0.0076 |
