Figure 8
500 µm slice simulation. (A). Snapshots from a movie (Suppl. Movie 1) illustrating a simulation of a 500 µm thick transversal slice stimulated from the CA3 side (white arrow). Each dot corresponds to a CA1 neuron/interneuron. The activation of a group of about 200 PCs (white spots on the left) by a single stimulus (t = 0 ms) induces a rapid transversal (Antero-posterior; A-P) invasion of the slice (t = 4,10 ms) which subsequently propagates longitudinally (medio-lateral; M-L). (B) Similarly to (A), stimulation of the slice from the subiculum side (white arrow). preferentially activates PCs whose activity remains confined to the subiculum side with little longitudinal propagation. Images have been generated through the software Vsimpl60. Scale bar 100 µm. A neuron’s activity is color coded from blue (rest) to white (spike), to visualize action potentials, with a fixed 2 ms transition time.
