Table 2 Comparison of clinicopathological factors between the asymptomatic and symptomatic groups according to subtype.

From: Prognosis of asymptomatic versus symptomatic metastatic breast cancer: a multicenter retrospective study

 

Luminal

HER2

Triple negative

Asymptomatic MBC (n = 75)

Symptomatic MBC (n = 45)

Asymptomatic MBC (n = 27)

Symptomatic MBC (n = 23)

Asymptomatic MBC (n = 12)

Symptomatic MBC (n = 22)

Agea, years

62 (36–88)

59 (26–91)

56 (36–77)

56 (31–82)

56 (41–81)

59 (26–88)

Recurrence-free survival, months

46 (13–237)

54 (5–309)

54.5 (7–182)

54.5 (13–210)

20 (4–108)

22 (4–71)

Visceral metastasisa

49 (65.3%)

23 (51.1%)

16 (59.3%)

15 (65.2%)

5 (41.7%)

10 (45.5%)

Multiple metastatic sitesa

28 (37.3%)

25 (55.6%)

8 (29.6%)

13 (56.5%)

4 (33.3%)

10 (45.5%)

Metastasis siteb

Lung

33

15

9

8

4

6

Bone

29

20

9

7

2

9

Lymph node

20

19

7

7

6

10

Liver

22

6

8

7

2

2

Chest wall

0

5

2

6

1

6

Brain

3

5

1

1

0

1

Stage 0/1/2/3/Unknown

0/14/30/28/3

0/4/28/12/1

1/6/8/11/1

0/4/7/9/2

0/2/6/4

0/4/13/5

  1. HER2 human epidermal growth factor receptor 2, MBC metastatic breast cancer, OS overall survival, PRS post-recurrence survival.
  2. aAt the time of confirmation of metastasis.
  3. bThere are duplicate cases.
  4. p-value less than 0.05.
  5. p-value greater than 0.05, less than 0.1.