Figure 2 | Scientific Reports

Figure 2

From: New definitions of human lymphoid and follicular cell entities in lymphatic tissue by machine learning

Figure 2

Movement and morphology of lymphocytes in human lymphoid tissue. Column A describes the analysis of the lymphocyte motility based on cell tracks. (A.1) visualizes the definition of the inspected features, turning angle and step size per time frame, later called velocity. (A.2) shows the results of the analysis. Column B describes the morphological analysis of lymphocytes based on cell tracks. (B.1) displays the features used for morphological descriptions, ellipse, to represent the eccentricity and major axis, later defined as cell size. On the upper left of (B.2), the size of each cell type is visualized. Conclusively, column C displays the analysis of CD35 positive follicular dendritic cells (FDC). (C.1) visualizes the major concept of optical flow to determine on spot FDC velocity. (C.2) shows the positive correlation of FDC velocity related to lymphocyte velocity in the microenvironment.

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