Figure 4

The definition of motion-specific subsets of cell types. The so called data-driven clusters (DD-cluster), directed and undirected, are based on eight most discriminative features derived from binary logistic regression experiment CD20 vs CD3, shown in (A). (B) displays the composition of DD-clusters per cell type, defined by unsupervised machine learning. Conclusively, (C–E) visualize the data enrichment based on movement and machine learning. (C) shows information given by conventional immunohistochemistry. (D) visualizes the information given by immunohistochemistry enriched with movement and computer vision. (E) visualizes information facilitating immunohistochemistry, movement, computer vision and machine learning.