Figure 5
From: A lignan from Alnus japonica inhibits glioblastoma tumorspheres by suppression of FOXM1
Therapeutic effects of DFS in orthotopic xenograft models. (A,B) Tumor volumes of orthotopic xenograft models measured by magnetic resonance imaging (MRI). (C) Kaplan–Meier analysis of survival probability of each group of mice, with comparisons by log-rank tests (P < 0.05) with Bonferroni adjustment. (D,E) To identify invading cells, section of the brains of killed mice were immunostained for Zeb1. From 10 photos captured for each mouse, the number of infiltrating Zeb+ cells (outside the red line in (D)) was tallied for each group (means ± SEM; *P < 0.01 compared with control). (F) Schematic summary of the study.
