Figure 4 | Scientific Reports

Figure 4

From: LINE-1 and Alu methylation signatures in autism spectrum disorder and their associations with the expression of autism-related genes

Figure 4

Genomic location and specificity of the unique differentially methylated regions in ASD with 16p11.2 deletion. Genomic location on XK related 6 (XKR6) (a), Zinc Finger Protein 107 (ZNF107) (b) and Myeloma overexpressed 2 (MYEOV2) (c): blue line represents hypomethylation, red line represents hypermethylation. The receiver operating characteristic (ROC) analysis of the unique differentially methylated regions of ASD with 16p11.2 deletion (n = 7) was performed against non-ASD (n = 48) and ASD with CHD8 variants (n = 15). Specificity and sensitivity of the unique differentially methylated regions for XKR6 (d), ZNF107 (e) and MYEOV2 (f).

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