Table 1 Group-wise demographic and clinical characteristics of all patients included in 24-h EDA pattern analysis.

From: Seizure-related differences in biosignal 24-h modulation patterns

 

No-seizure group (n = 68)

Seizure group (n = 49)

p-value

Sex

0.098

Male

30 (44.1%)

30 (61.2%)

 

Female

38 (55.9%)

19 (38.8%)

 

Age at enrollment

0.019

In years, median (IQR, p25-p75)

9.4 (8.4, 7.0–15.4)

13.2 (7.2, 9.6–16.8)

 

Age at First Seizure

0.021

In years, median (IQR, p25-p75)

3.5 (5.9, 1.1–7.0)

7.0 (8.5, 2.0–10.5)

 

Seizure frequency (estimated per 30 days)

0.839

No per month (IQR, p25-p75)

4.0 (20.3, 0.7–20.9)

4.0 (9.7, 1.0–10.7)

 

Etiology of epilepsy

0.219

Structural

22 (32%)

23 (47%)

 

Unknown

36 (53%)

20 (41%)

 

Genetic

6 (9%)

3 (6%)

 

Immune

1 (2%)

2 (4%)

 

Infectious

0 (0%)

1 (2%)

 

Metabolic

0 (0%)

0 (0%)

 

Not Reported

3 (4%)

0 (0%)

 

Interictal EEG*

 

Normal

18 (26%)

4 (8%)

0.097

Spikes

55 (81%)

43 (88%)

0.320

Focal Slowing

14 (21%)

23 (47%)

0.002

Generalized Slowing

10 (15%)

0 (0%)

0.005

MRI Findings

0.050

Normal

20 (29%)

6 (12%)

 

Abnormal

33 (49%)

25 (51%)

 

Not done/not available

15 (22%)

18 (37%)

 

Reduction of at least 1 ASM during EMU stay

0.001

Yes

18 (26%)

31 (63%)

 

No

46 (68%)

18 (37%)

 

Not available

4 (6%)

0 (0%)

 

Wristband Location**

0.350

Left wrist

18

13

 

Left ankle

18

18

 

Left unavailable

3

0

 

Right wrist

17

13

 

Right ankle

11

4

 

Right unavailable

1

0

 

Unavailable

0

1

 

Recording length in hours (after 10 min segment exclusion)

0.014

Mean (p25-p75)

20.94 (18.5–23.0)

19.33 (17.0–21.3)

 
  1. We calculated Chi-square tests for categorical and Mann–Whitney-U tests for continuous variables to compare groups.
  2. *Patients with interictal abnormalities may have had more than one abnormality.
  3. **If two wristbands were placed, we included one recording and preferred left wrist, over right wrist, over ankle recordings.