Table 1 Precision and recovery of horse whole blood spheroids analysis by PS-MS/MS.
Spiked creatinine concentrations | ||||
|---|---|---|---|---|
0 μg/mL | 2.5 μg/mL | 5 μg/mL | 10 μg/mL | |
Intra-day precision (n = 5) | ||||
Average peak area ratio | 0.649 | 0.850 | 1.024 | 1.423 |
SD | 0.023 | 0.016 | 0.044 | 0.034 |
CV, % | 3.6 | 1.9 | 4.3 | 2.4 |
Interday precision (n = 4 / day, 3 days) | ||||
Average peak area ratio | 0.657 | 0.847 | 1.034 | 1.383 |
SD | 0.034 | 0.037 | 0.038 | 0.087 |
CV, % | 5.2 | 4.3 | 3.7 | 6.3 |
Recovery (n = 3) | ||||
Measured total spiked and blood amount (μg/mL) | 8.03 | 10.22 | 12.62 | 17.47 |
SD | 0.21 | 0.11 | 0.05 | 0.86 |
Measured spiked amount (μg/mL) | 2.19 | 4.58 | 9.44 | |
SD | 0.14 | 0.05 | 0.86 | |
Recovery, % | 88 | 92 | 94 | |
CV, % | 4.5 | 0.9 | 8.6 | |
