Figure 1
From: H-ABC tubulinopathy revealed by label-free second harmonic generation microscopy

The supernumerary microtubules in mutant oligodendrocytes could emit detectable second harmonic signal. (A) Schematic setup of the commercial microscope used for imaging. NDD: non-descanned, PMT: Photomultiplier NA: Numerical aperture. (B) The healthy nervous system does not generate detectable second harmonic signal. (C) The pathologic white matter of the taiep rat emits second harmonic signal.