Figure 13 | Scientific Reports

Figure 13

From: Bioinformatics analyses of potential ACLF biological mechanisms and identification of immune-related hub genes and vital miRNAs

Figure 13

Experimental validation by establishing an ACLF rat model. (A) Pathological damage in rat liver observed by HE and Masson staining (Scale bars: 100 μm). (B) Liver sections were co-stained with iba1 (macrophages marker) and CD68 (M1 marker) (Scale bars: 50 μm, × 400). (C) Quantitative analysis of CD68 + /iba1 + macrophages in each field. The expression levels of hub gene (D) as well as miRNA (E) in ACLF rats were measured with qRT-PCR. *p < 0.05, **p < 0.01 and ***p < 0.001.

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