Figure 4 | Scientific Reports

Figure 4

From: Developmental RNA-Seq transcriptomics of haploid germ cells and spermatozoa uncovers novel pathways associated with teleost spermiogenesis

Figure 4

Protein–protein interaction (PPI) networks of DEGs. The PPI information of DEGs potentially involved in transcription and translation and chromatin organization (a), and metabolism (b), was obtained through a database search using STRING database v11 with a high confidence score (0.9), and imported into Cytoscape v3.8.2 (https://cytoscape.org/) for network construction and plotting. Proteins and their interactions are shown as nodes (spheres) and edges (lines), respectively. Nodes in red or green color indicate upregulated and downregulated DEGs, respectively. Proteins are grouped based on their known biological functions. OXPHOS, oxidative phosphorylation; PPP, pentose phosphate pathway; TCA, tricarboxylic acid.

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