Table 1 Baseline demographic and clinical characteristics.

From: Delirium severity does not differ between medical and surgical intensive care units after adjusting for medication use

Demographic and clinical characteristics

Total sample (n = 474)

SICU (n = 121)

MICU (n = 353)

P value

Mean [SD]

Agea

59 [16]

54 [19]

61 [14]

 < 0.001

Education (years)

11.56 [2.25]

11.53 [2.20]

11.57 [2.27]

0.88

Illness severity (APACHE II)a

20.14 [8.34]

16.77 [7.84]

21.27 [8.19]

 < 0.001

Charlson Comorbidity Index (CCI)a

3.00 [2.74]

1.77 [2.41]

3.42 [2.72]

 < 0.001

Premorbid cognition (IQCODE)a

3.19 [0.45]

3.14 [0.37]

3.20 [0.47]

0.005

Premorbid function (iADL)a

6.29 [2.46]

7.08 [1.93]

6.02 [2.57]

 < 0.001

No. [%] with data

Femalea

256 (54)

52 (43)

204 (58)

0.006

Black

210 (45)

55 (45)

155 (44)

0.83

Mechanical ventilation

385 (81)

100 (83)

285 (81)

0.69

Haloperidol eligible arma,b

298 (63)

88 (73)

210 (59)

0.009

Randomized to interventionc

237 (50)

63 (52)

174 (49)

0.67

  1. This table presents the study demographics and clinical characteristics of the overall cohort and in each ICU setting.
  2. APACHE II illness severity, IADL instrumental activities of daily living (Lawton), ADL activities of daily living (Katz), SICU surgical intensive care unit, MICU medical intensive care unit, CCI Charlson Comorbidity Index, IQCODE informant questionnaire on cognitive decline in the elderly.
  3. aStatistically significant differences between MICU and SICU.
  4. bHaloperidol Eligible Arm refers to the patients without contraindications to the haloperidol intervention for the PMD study.
  5. cRandomized to Intervention refers to the patients assigned to either haloperidol prescribing arm or the de-prescribing only arm of the PMD and de-PMD studies, respectively, as opposed to usual care.
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