Table 2 Sedative, opioid, and psychotropic medication use.

Medication daily dose in Mg	Total sample (n = 474)	SICU (n = 121)	MICU (n = 353)	P value
Median [IQR]
Lorazepam equivalents^a	0.4 [0.0, 3.70]	1.1 [0.0, 10.50]	0.3 [0.0, 2.00]	0.007
Propofol	0.0 [0.0, 271.60]	0.0 [0.0, 127.5]	0.0 [0.0, 272.4]	0.52
Dexmedetomidine	0.0 [0.0, 0.0]	0.0 [0.0, 0.0]	0.0 [0.0, 0.0]	0.38
Haloperidol	0.0 [0.0, 0.6]	0.0 [0.0, 1.3]	0.0 [0.0, 0.4]	0.06
Quetiapine^a	0.0 [0.0, 0.0]	0.0 [0.0, 0.0]	0.0 [0.0, 0.0]	< 0.001
Risperdal	0.0 [0.0, 0.0]	0.0 [0.0, 0.0]	0.0 [0.0, 0.0]	0.09
Olanzapine	0.0 [0.0, 0.0]	0.0 [0.0, 0.0]	0.0 [0.0, 0.0]	0.50
Clonidine	0.0 [0.0, 0.0]	0.0 [0.0, 0.0]	0.0 [0.0, 0.0]	0.06
Morphine equivalents^a	32.6 [3.4, 100.3]	56.7 [5.4, 149.0]	29.2 [2.5, 92]	0.002
Any medication use in first 7 days
No. (%) with data
Lorazepam equivalents	309 (65)	83 (69)	226 (64)	0.38
Propofol	186 (39)	43 (36)	143 (41)	0.39
Dexmedetomidine	41 (9)	13 (11)	28 (8)	0.35
Haloperidol	170 (36)	48 (40)	122 (35)	0.32
Quetiapine^a	37 (8)	21 (17)	16 (5)	< 0.001
Risperdal	1 (.2)	1 (1)	0 (0)	0.26
Olanzapine	7 (2)	1 (1)	6 (2)	0.68
Clonidine	24 (5)	10 (8)	14 (4)	0.09
Morphine equivalents	414 (87)	112 (92)	302 (86)	0.06

This table presents doses of sedative, opioid, and psychotropic medications compared between SICU and MICU, expressed as medication daily dose and number of patients who received that medication during the first 7 days.
SICU surgical intensive care unit, MICU medical intensive care unit, Mg milligrams, IQR interquartile range, No. number.
^aStatistically significant differences between MICU and SICU.

Quick links

Search