Figure 3
From: State space methods for phase amplitude coupling analysis

The phase amplitude coupling profile of a subject infused with increasing target effect site concentrations of propofol. Left: response probability curves (a) aligned with modulograms (c) (distribution of alpha amplitude with respect to slow phase) computed with standard (top) and state-space parametric (bottom) methods. Right: propofol infusion target concentration (b) aligned with corresponding modulation indices (d). Standard technique significance was assessed using 200 random permutations and CI where estimated using \(200\times 200\) samples.