Table 6 Pharmacokinetic parameters of alcohol and its metabolites in human blood (\(\overline{{\text{x}}}\) ± S, min–max, n = 26).
From: Estimating the time of last drinking from blood ethyl glucuronide and ethyl sulphate concentrations
Parameter | Alcohol | EtG | EtS |
|---|---|---|---|
AUC(0–t) (mg/L*) | 1715.23 ± 626.72 (505.00–2914.00) | 1.99 ± 0.78 (0.76–3.55) | 1.04 ± 0.34 (0.41–1.75) |
t1/2z (h) | 1.24 ± 1.09 (0.30–4.23) | 2.56 ± 0.89 (1.03–4.94) | 2.04 ± 0.76 (1.11–3.32) |
Tmax (h) | 2.02 ± 0.54 (1.50–3.00) | 4.12 ± 1.07 (2.00–5.00) | 3.02 ± 0.70 (1.50–5.00) |
Cmax (mg/L) | 441.65 ± 113.86 (238.20–656.00) | 0.31 ± 0.11 (0.13–0.53) | 0.17 ± 0.04 (0.08–0.28) |
Vz/F (L/kg) | 0.69 ± 0.49 (0.11–1.76) | – | – |
CLZ/F (L/h) | 0.49 ± 0.33 (0.17–0.43) | – | – |
