Table 1 Clinical characteristics of the 3780 patients with acute myocardial infarction stratified according to serum calcium concentration quartiles.
Characteristic | Serum calcium concentration quartile | ||||
---|---|---|---|---|---|
Ca-Q1 (n = 892) | Ca-Q2 (n = 997) | Ca-Q3 (n = 883) | Ca-Q4 (n = 1008) | P | |
Demographics | |||||
Age, years | 63.0 (55.0–70.0) | 61.0 (53.0–69.0) | 58.0 (50.0–67.0) | 57.0 (48.0–66.0) | < 0.001 |
Men (n, %) | 650 (72.9%) | 738 (74.0%) | 651 (73.7%) | 759 (75.3%) | 0.680 |
Current smoking (n, %) | 473 (53.0%) | 546 (54.8%) | 448 (50.7%) | 563 (55.9%) | 0.132 |
Current alcohol use (n, %) | 90 (10.1%) | 105 (10.5%) | 98 (11.1%) | 132 (13.1%) | 0.159 |
Medical history | |||||
Hypertension (n, %) | 268 (30.0%) | 416 (41.7%) | 418 (47.3%) | 506 (50.2%) | < 0.001 |
Diabetes mellitus (n, %) | 156 (17.5%) | 208 (20.9%) | 184 (20.8%) | 211 (20.9%) | 0.180 |
Stroke (n, %) | 84 (9.4%) | 77 (7.7%) | 71 (8.0%) | 79 (7.8%) | 0.522 |
Hyperlipidemia (n, %) | 68 (7.6%) | 141 (14.1%) | 174 (19.7%) | 206 (20.4%) | < 0.001 |
In-hospital complications | |||||
Acute heart failure (n, %) | 97 (10.9%) | 134 (13.4%) | 117 (13.3%) | 133 (13.2%) | 0.304 |
Acute arrhythmia (n, %) | 30 (3.4%) | 44 (4.4%) | 38 (4.3%) | 47 (4.7%) | 0.528 |
Medication on admission | |||||
ACEI/ARB (n, %) | 445 (49.9%) | 497 (49.8%) | 462 (52.3%) | 500 (49.6%) | 0.621 |
Beta-blocker (n, %) | 511 (57.3%) | 569 (57.1%) | 521 (59.0%) | 560 (55.6%) | 0.514 |
Aspirin (n, %) | 621 (69.6%) | 726 (72.8%) | 621 (70.3%) | 703 (69.7%) | 0.367 |
Statin (n, %) | 713 (79.9%) | 768 (77.0%) | 708 (80.2%) | 780 (77.4%) | 0.205 |
Main diagnosis | |||||
NSTEMI (n, %) | 280 (31.4%) | 308 (30.9%) | 266 (30.1%) | 312 (31.0%) | 0.168 |
STEMI (n, %) | 612 (68.6%) | 689 (69.1%) | 617 (69.9%) | 696 (69.0%) | 0.025 |
Reperfusion strategy | |||||
PCI (n, %) | 345 (38.7%) | 431 (43.2%) | 358 (40.5%) | 404 (40.1%) | 0.228 |
Thrombolysis (n, %) | 191 (21.4%) | 215 (21.6%) | 203 (23.0%) | 202 (20.0%) | 0.486 |
Laboratory results | |||||
Albumin (g/L) | 37.4 (34.9–39.8) | 38.5 (36.5–40.9) | 39.3 (37.0–41.6) | 40.1 (37.7–42.6) | 0.651 |
BUN (mmol/L) | 6.0 (4.8–7.6) | 5.8 (4.8–7.0) | 5.7 (4.6–6.8) | 5.5 (4.6–6.9) | 0.017 |
Total cholesterol (mmol/L) | 4.4 (3.6–5.2) | 4.5 (3.7–5.2) | 4.7 (3.7–5.7) | 4.8 (3.9–5.8) | 0.517 |
Total triglycerides (mmol/L) | 1.6 (1.0–2.4) | 1.8 (1.2–3.2) | 2.0 (1.3–3.7) | 2.0 (1.3–3.3) | 0.674 |
HDL-C (mmol/L) | 1.2 (1.0–1.4) | 1.2 (1.1–1.4) | 1.3 (1.1–1.5) | 1.2 (1.0–1.4) | 0.032 |
LDL-C (mmol/L) | 3.0 (2.4–3.7) | 3.2 (2.6–3.8) | 3.3 (2.8–3.9) | 3.4 (2.7–4.1) | 0.766 |
Fasting glucose (mmol/L) | 8.0 (6.3–11.0) | 7.9 (6.3–10.5) | 7.9 (6.5–10.2) | 7.7 (6.4–10.5) | 0.408 |
Serum creatinine (µmol/L) | 81.0 (68.4–97.9) | 81.1 (69.2–94.5) | 79.8 (70.1–92.3) | 78.0 (68.7–91.0) | < 0.001 |
Uric acid (µmol/L) | 305.5 (256.5–367.4) | 314.4 (272.4–366.4) | 317.4 (276.7–363.5) | 323.7 (276.0–382.5) | < 0.001 |
Serum phosphate (mmol/L) | 1.1 (0.9–1.4) | 1.1 (1.0–1.2) | 1.1 (1.0–1.2) | 1.1 (1.0–1.2) | 0.028 |
Serum magnesium (mmol/L) | 0.9 (0.8–1.0) | 0.9 (0.8–0.9) | 0.9 (0.8–0.9) | 0.9 (0.8–0.9) | 0.028 |
Serum potassium (mmol/L) | 3.9 (3.6–4.3) | 4.0 (3.7–4.3) | 4.0 (3.7–4.2) | 4.0 (3.8–4.3) | 0.055 |
Serum sodium (mmol/L) | 137.6 (134.7–140.1) | 138.3 (135.7–141.0) | 138.8 (136.0–141.4) | 139.2 (136.3–141.7) | 0.463 |
Serum chloride (mmol/L) | 101.8 (99.0–104.2) | 101.7 (99.3–104.2) | 101.6 (99.4–103.8) | 101.5 (98.9–104.0) | 0.018 |
Echocardiography results | |||||
LVEF (%) | 49.0 (41.0–56.0) | 50.0 (43.0–56.0) | 50.0 (43.6–56.0) | 51.0 (44.2–56.9) | 0.010 |
LAD (mm) | 37.0 (35.0–40.0) | 37.0 (34.8–39.0) | 36.7 (34.7–39.0) | 36.4 (34.0–39.0) | 0.047 |
LVEDD (mm) | 51.0 (47.6–54.0) | 50.8 (47.0–53.9) | 50.0 (47.0–53.5) | 50.0 (47.0–53.0) | 0.248 |
Temperature information | |||||
Daily maximum temperature | 11.42 (14.91) | 11.32 (14.61) | 9.61 (14.85) | 9.19 (15.21) | < 0.001 |
Daily minimum temperature | 1.05 (14.30) | 1.05 (14.05) | −0.49 (14.19) | −1.12 (14.70) | < 0.001 |
Daily mean temperature | 6.09 (14.57) | 6.08 (14.26) | 4.44 (14.47) | 3.92 (14.89) | < 0.001 |
Main index and outcome measure | |||||
DTR ( °C) | 10.0 (7.6–12.8) | 9.9 (7.7–12.5) | 9.8 (7.5–12.4) | 10.0 (7.8–12.6) | 0.426 |
In-hospital mortality (n, %) | 84 (9.4%) | 46 (4.6%) | 43 (4.9%) | 15 (1.5%) | < 0.001 |