Table 7 Biomarker and clinical evaluation levels at admission among survivors and diseased at 180-days for the whole group (sepsis and non-sepsis). Mann U Whitney test. (In the septic shock group, 24/100 patients had deceased at 180-days and in the non-sepsis group, 25/64 patients had deceased at 180-days). Bonferroni corrected p value for 9 comparisons.
From: Hepcidin discriminates sepsis from other critical illness at admission to intensive care
Biomarker | Survivors (n = 115) | Deceased (n = 49) | p value | Adjusted p value |
|---|---|---|---|---|
Hepcidin, nmol/L (IQR) | 37.0 (16.0–64.0) | 14.0 (5.0–40.0) | < 0.001 | < 0.001 |
HBP, ng/mL (IQR) | 34.8 (29.3–85.6) | 38.2 (20.6–83.3) | 0.467 | 1.00 |
CRP, mg/L (IQR) | 142.0 (116.8–342.0) | 100.0 (19.5–153.0) | 0.013 | 0.117 |
PCT, µg/L (IQR) | 18.0 (1.2–68.0) | 3.6 (0.8–30.5) | 0.046 | 0.414 |
Lactate, mmol/L (IQR) | 2.2 (1.2–3.7) | 3.3 (1.6–7.0) | 0.011 | 0.099 |
WBC, × 109/L (IQR) | 11.2 (7.5–18.5) | 13.0 (9.2–19.2) | 0.361 | 1.00 |
SOFA (IQR) | 9.0 (6.0–11.0) | 11.0 (9.0–13.0) | 0.001 | 0.009 |
SAPS 3 (IQR) | 62.0 (54.8–70.0) | 79.0 (71.0–84.0) | < 0.001 | < 0.001 |
Body temperature | 37.0 (36.4–38.4) | 36.5 (35.7–37.5) | 0.003 | 0.027 |
