Table 8 Results from logistic regressions where 28-day mortality is set as the dependent variable, predicted by arrival values of biomarkers, SOFA or SAPS 3. An interaction model was used to account for different effects in the Sepsis/Non-Sepsis group. Odds ratio (OR) presented with 95% confidence interval. CRP C-reactive protein, HBP heparin-binding protein, PCT procalcitonin, WBC white blood cells, SOFA Sequential Organ Failure Assessment, SAPS3 Simplified acute physiology score III.
From: Hepcidin discriminates sepsis from other critical illness at admission to intensive care
Predictor | Sepsis | Non-sepsis | ||
---|---|---|---|---|
p value | OR (95% CI) | p value | OR (95% CI) | |
Hepcidin | 0.147 | 0.987 (0.969–1.005) | 0.470 | 0.990 (0.965–1.017) |
HBP | 0.501 | 1.001 (0.999–1.003) | 0.580 | 1.001 (0.999–1.003) |
PCT | 0.828 | 0.999 (0.995–1.004) | 0.753 | 1.001 (0.995–1.006) |
CRP | 0.017 | 0.995 (0.991–0.999) | 0.034 | 0.996 (0.992–1.000) |
Lactate | < 0.001 | 1.289 (1.124–1.479) | < 0.001 | 1.279 (1.119–1.463) |
WBC | 0.362 | 1.015 (0.983–1.049) | 0.572 | 1.010 (0.977–1.044) |
SOFA | < 0.001 | 1.272 (1.121–1.445) | < 0.001 | 1.283 (1.129–1.457) |
SAPS3 | < 0.001 | 1.132 (1.083–1.183) | < 0.001 | 1.132 (1.083–1.182) |