Table 1 Baseline demographic and clinical characteristics of the study population.

From: Pulmonary pathophysiology development of COVID-19 assessed by serial Electrical Impedance Tomography in the MaastrICCht cohort

 

ICU survivors

(n = 51)

ICU non-survivors

(n = 29)

p-value for difference

Age, year

61.5 (11.9)

68.5 (9.9)

0.007

Sex, men

37 (72.5%)

25 (86.2%)

0.259

Body mass index, kg/m2

28.0 (4.4)

27.5 (4.0)

0.554

Chronic lung disease

2 (3.9%)

2 (6.9%)

0.618

APACHE II score, points

15.5 (5.1)

17.0 (4.7)

0.187

SOFA score, points

7.6 (2.6)

8.0 (2.2)

0.598

Admission ventilation variables

Mechanical ventilation, n

48 (94.1%)

26 (89.7%)

0.662

Pressure control ventilation, n

34 (66.7)

23 (79.3)

0.307

FiO2, %

73.1 (18.8)

78.7 (18.0)

0.206

Respiration rate, per minute

22.7 (3.8)

22.1 (4.2)

0.680

Inspiratory pressure, cmH2O

27.0 (4.3)

27.5 (3.5)

0.754

PEEP, cmH2O

11.8 (2.8)

11.3 (3.4)

0.475

PaO2/FiO2-ratio

184.3 (61.4)

151.3 (54.4)

0.017

Tidal volume, ml/kg PBW

6.7 (1.1)

6.2 (1.2)

0.181

Arterial blood gas PaO2, kPa

10.5 (3.3)

10.4 (3.7)

0.876

Arterial blood gas PaO2, mmHg

79.0 (25.0)

78.0 (27.4)

0.876

Arterial blood gas PaCO2, kPa

5.9 (1.6)

6.3 (1.6)

0.399

Arterial blood gas PaCO2, mmHg

44.5 (12.1)

46.9 (12.1)

0.399

Arterial blood gas pH

7.36 (0.15)

7.28 (0.12)

0.025

Mean arterial blood pressure, mmHg

101.7 (12.7)

96.5 (15.6)

0.134

Outcome variables

Length of mechanical ventilation, days

22.8 (13.8)

15.0 (9.9)

0.006

  1. Data are means SD, median (IQR), and percentages as appropriate. ICU, Intensive Care Unit; APACHE II, Acute Physiology And Chronic Health Evaluation II; SOFA, serial organ failure assessment; FiO2, fraction of inspired oxygen; PEEP positive end-expiratory pressure; PBW, predicted body weight; PaO2/FiO2-ratio, oxygen arterial partial pressure on inspired fraction of oxygen ratio; PaO2, oxygen arterial partial pressure; PaCO2, carbon dioxide arterial partial pressure.
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