Table 1 Subject characteristics of the CHD cases and controls.

From: Association between maternal smoke exposure and congenital heart defects from a case–control study in China

Characteristics

Cases

Controls

χ2

p value

No

%

No

%

Maternal age (years)

    

114.03

< 0.001

< 25

167

22.30

46

5.23

  

25–29

346

46.19

424

48.18

  

30–34

170

22.70

304

34.55

  

≥ 35

66

8.81

106

12.05

  

Maternal education level

    

222.12

< 0.001

≤ 9 school years

142

18.96

27

3.07

  

10–12 school years

153

20.43

51

5.80

  

13–16 school years

392

52.34

649

73.75

  

≥ 17 school years

62

8.28

153

17.39

  

Residence

    

214.96

< 0.001

Urban

428

57.14

783

88.98

  

Rural

321

42.86

97

11.02

  

Congenital anomalies family history

    

13.66

< 0.001

No

645

86.11

808

91.82

  

Yes

104

13.89

72

8.18

  

Maternal folate intakea

    

52.83

< 0.001

Yes

309

41.26

522

59.32

  

No

440

58.74

358

40.68

  

Maternal HNS exposureb

    

38.99

< 0.001

No

445

59.41

651

73.98

  

Yes

304

40.59

229

26.02

  

Paternal smokingc

    

24.90

< 0.001

No

429

57.28

609

69.20

  

Yes

320

42.72

271

30.80

  
  1. aTaking folic acid over 90 days or more during the 3 months before conception to the first trimester.
  2. bMaternal HNS (maternal hazardous and noxious substances) exposure during the 3 months before conception to the first trimester.
  3. cPaternal smoking during 0–3 months before conception.