Table 2 Occlusion analysis.

From: Mapping the association between tau-PET and Aβ-amyloid-PET using deep learning

Cluster number

Label

Areas

Post-occlusion R2 (training)

Post-occlusion R2 (validation)

Post-occlusion R2 (testing)

 

AC

All clusters

0.16

0.02

− 0.05

1

MTR

Right hippocampus, right parahippocampal gyrus, right amygdala, right fusiform

0.51

0.43

0.15

2

FPC

Bilateral frontal lobe, precentral gyri, supplementary motor areas, paracentral lobules, superior & inferior parietal lobules, precuneus, postcentral gyri & middle cingulate

0.84

0.84

0.64

3

MTL

Left hippocampus, left parahippocampal gyrus, left amygdala, left fusiform

0.84

0.74

0.59

4

OL

Lingual gyri, calcarine sulci

0.96

0.95

0.80

5

IL

Left Insula

0.97

0.96

0.79

  1. Correlation between measured and CNN-estimated Aβ CL values for training (n = 109), validation (n = 12) and test (n = 13) datasets, shown before and after removal of salient clusters. The original R2 values before the occlusion were 0.97, 0.96 and 0.79 for training, validation and test datasets, respectively.
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