Figure 5 | Scientific Reports

Figure 5

From: No evidence for carcinogenicity of titanium dioxide nanoparticles in 26-week inhalation study in rasH2 mouse model

Figure 5

Examination for cell proliferative activity in alveolar epithelial type 2 cell (AEC2). Representative immunohistochemical staining images of Ki67, a cell proliferation marker, and lysophosphatidylcholine acyltransferase 1 (LPCAT1), an AEC2 marker (A). The Ki67-positive index in AEC2 was calculated as the percentage of Ki67 and LPCAT1 double positive cells to total LPCAT1-positive cells (B). Lesion, inflammatory foci; SUR, lesion-surrounding tissue; n.s, not significant.

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