Figure 4
From: Computational model predicts the neural mechanisms of prepulse inhibition in Drosophila larvae
Dependence of PPI on the lead interval. (a) Temporal changes in neuron activity (\({\mathrm{w}}_{\text{iLNa}}=1.10,{\mathrm{w}}_{{\text{iL}}{\text{Nb}}}=2.40\)) as the lead interval changed. Upper left: Without a prepulse. Upper right: Lead interval of 10 time units. Lower left: Lead interval of 30 time units. Lower right: Lead interval of 50 time units. A vertical dashed black line indicates the time of the pulse input. The thin arrow head pointing to the horizontal axis indicates the prepulse timing, and the thick arrow head indicates the pulse timing. The red and blue colours indicate the onset and offset times, respectively. The colours in the band below each graph indicate the behaviour at the corresponding time. Green: n.r. Red: hunch. Behaviours indicated by the striped lines are classified as n.r. because their duration was shorter than the cut-off time (10 time units). (b) Changes in percentages of the startle response in the behavioural landscape due to changes in the lead interval. (c) Behavioural experimental results of changes in the startle response due to changes in the lead interval. Reprinted from Matsumoto et al.31 Fig. 1F.
