Figure 5

(A) Histological immunohistochemistry quantification analysis for collagen type I, integrin 1β and bone sialoprotein for the 3 groups ex-vivo samples after a 2-month transplantation period in balb/c nude mice. (B) A semi-quantification analysis was performed for the 3 protein markers and the PAR1 activation group showed greater staining for the 3 osteogenic protein markers after 60 days. Images at 10x. (*) p < 0.05. Results are given as the mean ± SD.